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•The American College of Chest
Physicians (ACCP) and Society of Critical Care Medicine (SCCM) held a consensus
conference in August 1991 to agree on a set of definitions that could be
applied to patients with sepsis and organ dysfunction. The consensus panel also
recommended the use of severity scoring methods to characterize the disease and
develop a comprehensive model for the syndrome.
•This slide provides a brief
definition of the various components of the sepsis syndrome. Notably, this is a
non-linear process rather than a continuum and the presence of organ
dysfunction identifies a population with a significant risk of mortality.
Bone RC, Balk RA, Cerra FB, et al. Definitions for
sepsis and organ failure and guidelines for the use of innovative therapies in
sepsis. Chest. 1992;101:1644-55.
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